Back Nontraditional Inheritance Inheritance patterns that do not fall into the chromosomal, single-gene, or multifactorial categories, are referred to as "nontraditional." Listed in the directory below are some examples, for which we have provided a brief overview. Uniparental Disomy: Prader-Willi Syndrome, Angelman Syndrome Trinucleotide Repeats: Fragile-X Syndrome Mitochondrial Inheritance: Leber's Optic Atrophy